PubMed PMID: 27747960. 11: Jha AK, Sonthalia S, Sarkar R. Dermoscopy of discoid lupus erythematosus. OBJECTIVE: Systemic lupus erythematosus (SLE) is a chronic, relapsing-remitting autoimmune disorder that involves multiple organ systems including the central nervous system. Among the items included in the nomenclature for neuropsychiatric SLE, mood disorders have been identified.
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The combination of DH and SLE is immunologically mediated and suggests a relationship between the two conditions. We descr … Somers EC, Marder W, Cagnoli P, et al. Population-based Incidence and Prevalence of Systemic Lupus Erythematosus: The Michigan Lupus Epidemiology and Surveillance Program. Arthritis Rheumatol. 2014;66(2):369–378. doi:10.102/art.38238.
Merrill JT, Neuwelt CM, Wallace DJ, et al. Efficacy and safety of rituximab in moderately-to-severely active systemic lupus erythematosus: the randomized, double-blind, phase II/III systemic lupus erythematosus evaluation of rituximab trial. Sunscreens with a sun protection factor (SPF) >15 should be recommended to all SLE patients as are highly effective in preventing development of skin lesions.
Lupus. 2016 Sep 27. pii: 0961203316668041.
Morbidity and mortality in systemic lupus erythematosus during a 5 year period. A multicentre prospective study of 1000 patients. European Working Party on Systemic Lupus Erythematosus. Systemic lupus erythematosus develops in approximately one-quarter of patients with discoid lupus erythematosus within months to decades of the diagnosis of skin disease. Discoid lupus erythematosus may leave permanent scars, even when the active disease has responded to treatment. Duron L, Cohen-Aubart F, Diot E, et al. Shrinking lung syndrome associated with systemic lupus erythematosus: a multicenter collaborative study of 15 new cases and a review of the 155 cases in the literature focusing on treatment response and long-term outcomes.
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2011-09-30 · Systemic lupus erythematosus (SLE) is a complex disease characterized by the appearance of autoantibodies against nuclear antigens and the involvement of multiple organ systems, including the kidneys. The precise immunological events that trigger the onset of clinical manifestations of SLE are not yet well understood. However, research using various mouse strains of spontaneous and inducible 2016-03-17 · Both systemic lupus erythematosus (SLE) and its treatments can contribute to increased mortality rates. The focus of this review is recent studies on mortality and comorbidities during the last 5 years from around the world. The authors conducted a literature review, using PUBMED, for articles relating to SLE mortality with a specific focus on literature published within the last 5 years.
Although the outlook for patients with SLE has greatly improved, many unmet needs remain, chief of which is the development of safer and more efficacious therapies. To develop innovative therapies, a far better
Chilblain lupus erythematosus, Hutchinson lupus, Lupus chilblains, MIM 614415, MIM 610448, Chilblain LE. Authoritative facts from DermNet New Zealand.
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12: Drehmer MN, Andrade D, Pereira IA, Marrero AR, Muniz YC, de Souza IR, Löfgren SE. Estrogen receptor alpha gene (ESR1) polymorphism can contribute to clinical findings in systemic lupus erythematosus patients. Lupus. 2016 Sep 27. pii: 0961203316668041. Background: Examining urban-rural differences can provide insights into susceptibility or modifying factors of complex diseases, yet limited data exist on systemic lupus erythematosus (SLE). Objective: To study SLE risk, manifestations and severity in relation to urban versus rural residence.